Water → HCID 178511480, 화합물
반응식
Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH2:11][C:12]#[N:13])(=O)=[O:9])=[CH:4][CH:3]=1.[ClH:14].[NH2:15][OH:16].[OH2:17].C([O-])([O-])=O.[Na+].[Na+]>C(O)C>[Cl:14][C:2]1[CH:3]=[CH:4][C:5]([S:8]([CH2:11][C:12](=[NH:13])[NH:15][OH:16])(=[O:9])=[O:17])=[CH:6][CH:7]=1참가 물질
6
실험 절차
50 g. (0.23 mole) of 4-chlorophenylsulfonylacetonitrile were dissolved in 1.5 liters of ethanol and 16 g. (0.23 mole) of hydroxylamine HCl in 150 ml. of water was added to this solution, followed by the addition of 14.4 g. (0.12 mole) of Na2CO3 in 150 ml. of water. This reaction mixture was stirred at room temperature overnight. 58 g. crude product were filtered off; this was recrystallized from about 2.5 liters of ethanol to give 40 g. of the product (70% yield).
후처리
- additionfollowed by the addition of 14.4 g
- filtrationcrude product were filtered off
- customthis was recrystallized from about 2.5 liters of ethanol
- customto give 40 g
출처 및 근거
- ORD 기록
- ord-cfb04106ce044c1b82b83425a88a2633
- 출처 데이터셋
- uspto-grants-1979_04
- 특허 번호
- US04148801
반응 노트
불러오는 중…