2,5-Dimethyl-1H-indole → 3-(4-Chloro-3-sulfamoylbenzoyl)-2,5-dimethylindole
반응식
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12].[CH3:15][C:16]1[NH:17][C:18]2[C:23]([CH:24]=1)=[CH:22][C:21]([CH3:25])=[CH:20][CH:19]=2.[Cl-].[Al+3].[Cl-].[Cl-]>ClC(Cl)C>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([C:24]2[C:23]3[C:18](=[CH:19][CH:20]=[C:21]([CH3:25])[CH:22]=3)[NH:17][C:16]=2[CH3:15])=[O:7])=[CH:4][C:3]=1[S:11](=[O:14])(=[O:13])[NH2:12]참가 물질
5
실험 절차
is obtained as described in Example 10 (a) from 10 g 4-chloro-3-sulfamoylbenzoyl chloride and 7.8 g 2,5-dimethylindole in dichloro-ethane in the presence of 12 g aluminum chloride. M.p. 248°-250° C.
후처리
- customis obtained
출처 및 근거
- ORD 기록
- ord-3d6c2c9aa8a744cf8b6d9ed661a2a213
- 출처 데이터셋
- uspto-grants-1979_05
- 특허 번호
- US04156732
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