Hydrochloric Acid → 5-Hydroxyindan-1,2,3-trione, monohydrate

반응식

Br[CH:2]1[C:10](=[O:11])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([OH:12])[CH:8]=2)[C:3]1=[O:13].Cl.CS(C)=[O:17]>>[OH2:11].[OH:12][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[C:3](=[O:13])[C:2](=[O:17])[C:10]2=[O:11]

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 679Dimethyl Sulfoxide

HCID 190342852-Bromo-5-hydroxyindan-1,3-dione

생성물 1

HCID 218031995-Hydroxyindan-1,2,3-trione, monohydrate

실험 절차

A solution of 0.01 mol of 2-bromo-5-hydroxyindan-1,3-dione in 10 ml dimethyl sulphoxide was heated to 80° C. for 30 minutes. 50 ml of a 1N hydrochloric acid solution was added, after which heating was continued for 30 minutes. The oily suspension obtained after cooling was extracted with ethyl ether. The organic phase was washed in water and dried over magnesium sulphate.