2-Amino-4-chlorophenol → 2-Acetylamino-4-chlorophenol

HRID 270071

반응식

HRID 270071 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[OH:9].[C:10](OC(=O)C)(=[O:12])[CH3:11]>CO>[Cl:8][C:6]1[CH:5]=[CH:4][C:3]([OH:9])=[C:2]([NH:1][C:10](=[O:12])[CH3:11])[CH:7]=1

참가 물질

4

반응물 2

HCID 72652-Amino-4-chlorophenolHCID 7918Acetic Anhydride

생성물 1

HCID 952582-Acetylamino-4-chlorophenol수율 80.8%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

To a suspension of 2-amino-4-chlorophenol (1.43 g, 10.0 mmol) in methanol was added acetic anhydride (0.945 mL, 10.0 mmol) and the reaction mixture was stirred at room temperature for 2 h. The volatiles were removed in vacuo to give the subtitled compound (1.5 g).

후처리

  1. customThe volatiles were removed in vacuo

출처 및 근거

ORD 기록
ord-40c22dff81724e1d9b69e1626f222a07
출처 데이터셋
uspto-grants-2008_11
특허 번호
US07449475B2

연결된 노트

불러오는 중…