Hydrogen Bromide → HCID 178419247, 화합물

HRID 27476

반응식

HRID 27476 반응식
Cl.O[CH2:3][C:4]1[N:5]=[CH:6][NH:7][C:8]=1[CH3:9].Cl.[NH2:11][CH2:12][CH2:13][SH:14].[BrH:15]>C(O)(=O)C>[BrH:15].[BrH:15].[CH3:9][C:8]1[N:7]=[CH:6][NH:5][C:4]=1[CH2:3][S:14][CH2:13][CH2:12][NH2:11]

참가 물질

5

반응물 3

HCID 260Hydrogen BromideHCID 9082Cysteamine HydrochlorideHCID 30847074-Methylimidazol-5-ylmethanolhydrochloride

생성물 1

HCID 178419247HCID 178419247, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A mixture of 4-hydroxymethyl-5-methylimidazole hydrochloride (15.0 g.), cysteamine hydrochloride (11.5 g.) and a solution of hydrogen bromide in acetic acid (48%, 225 ml.) was heated under reflux for 7 hours. Cooling afforded 4-methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrobromide (21.6 g.), m.p. 208°-211°.

후처리

  1. temperatureunder reflux for 7 hours
  2. temperatureCooling

출처 및 근거

ORD 기록
ord-2a452a56a7ab4ac4b8d9474109575249
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04221802

연결된 노트

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