4-Aminonaphthalene-1,8-dicarboxylic anhydride → 6-Amino-2-hydroxy-benzo[de]isoquinoline-1,3-dione

HRID 278993

반응식

HRID 278993 반응식
[CH:1]1[CH:10]=[C:9]2[C:11]([O:13][C:14](=O)[C:7]3=[C:8]2[C:3](=[C:4]([NH2:16])[CH:5]=[CH:6]3)[CH:2]=1)=[O:12].Cl.[NH2:18][OH:19]>N1C=CC=CC=1>[NH2:16][C:4]1[CH:5]=[CH:6][C:7]2[C:14](=[O:13])[N:18]([OH:19])[C:11](=[O:12])[C:9]3[C:8]=2[C:3]=1[CH:2]=[CH:1][CH:10]=3

참가 물질

4

반응물 2

HCID 809904-Aminonaphthalene-1,8-dicarboxylic anhydrideHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 158962456-Amino-2-hydroxy-benzo[de]isoquinoline-1,3-dione수율 97.4%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

4-Amino-1,8-naphthalic anhydride (0.2 g, 0.9 mmol) and hydroxylamine hydrochloride (0.1 g, 1.4 mmol) were reacted in pyridine (20 mL) following the procedure of Example 1 to give 0.2 g of the title compound, mp >360° C.;

출처 및 근거

ORD 기록
ord-5c6e1141e8ca4934b1d04089a796f586
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06362181B1

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