1-Indanone → 3-Bromo-1-indanone

HRID 279152

반응식

HRID 279152 반응식
[C:1]1(=[O:10])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.C1C(=O)N([Br:18])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[Br:18][CH:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:1](=[O:10])[CH2:2]1

참가 물질

4

반응물 2

HCID 67351-IndanoneHCID 67184N-bromobutanimide

생성물 1

HCID 117459123-Bromo-1-indanone

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

1-Indanone (1 g) and NBS (1.4 g) was mixed with dry CCl4 (20 ml). A catalytic amount of AlBN was added and the mixture was refluxed for 30 minutes and excited with light using 250 W lamp. The mixture was cooled in an ice bath and filtered. The filtrate was concentrated in an evaporator and used without further purification for the next step. Yield was 1.5 g.

후처리

  1. temperaturethe mixture was refluxed for 30 minutes
  2. temperatureThe mixture was cooled in an ice bath
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated in an evaporator
  5. customused without further purification for the next step

출처 및 근거

ORD 기록
ord-c54a0fd89f4a4e89ae60c4b36eb93b67
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06362211B1

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