Water → 1-Azido-1-(3-furyl)-1-(4-methyl-5-oxazolyl)ethane

HRID 2835

반응식

HRID 2835 반응식
[O:1]1[CH:5]=[CH:4][C:3]([C:6]([C:9]2[O:13][CH:12]=[N:11][C:10]=2[CH3:14])(O)[CH3:7])=[CH:2]1.C[Si]([N:19]=[N+:20]=[N-:21])(C)C.B(F)(F)F.O>C1C=CC=CC=1>[N:19]([C:6]([C:3]1[CH:4]=[CH:5][O:1][CH:2]=1)([C:9]1[O:13][CH:12]=[N:11][C:10]=1[CH3:14])[CH3:7])=[N+:20]=[N-:21]

참가 물질

6

반응물 4

HCID 962WaterHCID 6356Boron trifluorideHCID 78378AzidotrimethylsilaneHCID 97941531-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol

생성물 1

HCID 189362941-Azido-1-(3-furyl)-1-(4-methyl-5-oxazolyl)ethane

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol (1 g) was suspended in benzene (4 ml). Trimethylsilylazide (822 μl) was added followed by boron trifluoride diethyletherate (770 μl). The mixture was stirred overnight at room temperature, then poured into water and extracted to give the title compound.

후처리

  1. extractionextracted

출처 및 근거

ORD 기록
ord-d5df902db51f4973b3595b8e30064e32
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05731335

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