Water → N-cyclohexylidene-2,6-dimethoxy-4-methylaniline

HRID 2917

반응식

HRID 2917 반응식
[CH3:1][O:2][C:3]1[CH:9]=[C:8]([CH3:10])[CH:7]=[C:6]([O:11][CH3:12])[C:4]=1[NH2:5].[C:13]1(=O)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1.O>C1(C)C=CC=CC=1>[C:13]1(=[N:5][C:4]2[C:6]([O:11][CH3:12])=[CH:7][C:8]([CH3:10])=[CH:9][C:3]=2[O:2][CH3:1])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

참가 물질

5

반응물 3

HCID 962WaterHCID 7967CyclohexanoneHCID 124090902,6-Dimethoxy-4-methylaniline

생성물 1

HCID 18936522N-cyclohexylidene-2,6-dimethoxy-4-methylaniline

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

4.2 g of 2,6-dimethoxy-4-methylaniline are dissolved in 50 ml of toluene, 2.45 g of cyclohexanone are then added and the reaction mixture is heated at reflux for 18 hours. The water which is formed is removed as it is formed in the reaction mixture using a Dean and Stark apparatus. The toluene is evaporated and the oily N-cyclohexylidene-2,6-dimethoxy-4-methylaniline residue obtained is used without addition of purification in the following stage.

후처리

  1. temperaturethe reaction mixture is heated
  2. temperatureat reflux for 18 hours
  3. customis removed as it
  4. customis formed in the reaction mixture
  5. customThe toluene is evaporated

출처 및 근거

ORD 기록
ord-7722dbce85914723bdf979fd6d719ccd
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05731340

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