1,3-Dibromopropane → Dimethyl N-(3-Bromopropyl)iminodiacetate
반응식
Cl.[CH3:2][O:3][C:4](=[O:12])[CH2:5][NH:6][CH2:7][C:8]([O:10][CH3:11])=[O:9].C(N(CC)C(C)C)(C)C.[Br:22][CH2:23][CH2:24][CH2:25]Br>C1(C)C=CC=CC=1>[Br:22][CH2:23][CH2:24][CH2:25][N:6]([CH2:5][C:4]([O:3][CH3:2])=[O:12])[CH2:7][C:8]([O:10][CH3:11])=[O:9]참가 물질
5
반응 조건
- 온도
- 90 °C
실험 절차
A mixture of 1 mmol iminodiacetic acid dimethylester hydrochloride salt, 5 mmol N,N-diisopropyl-ethylamine and 3 mmol 1,3-dibromopropane in 2 mL toluene was stirred at 90° C. for 16 h and then chromatographed to provide the title compound as an oil.
후처리
- customchromatographed
출처 및 근거
- ORD 기록
- ord-53859d19f5084c73a9229630dac0c84d
- 출처 데이터셋
- uspto-grants-1998_03
- 특허 번호
- US05731432
반응 노트
불러오는 중…