Hydrochloric Acid → 4-Borono-3-methoxybenzoic acid
반응식
O.[OH-].[Li+].C([O:6][C:7]([C:9]1[CH:14]=[CH:13][C:12]([B:15]([OH:17])[OH:16])=[C:11]([O:18][CH3:19])[CH:10]=1)=[O:8])C.O.Cl>O1CCOCC1>[C:7]([C:9]1[CH:14]=[CH:13][C:12]([B:15]([OH:17])[OH:16])=[C:11]([O:18][CH3:19])[CH:10]=1)([OH:8])=[O:6]참가 물질
6
실험 절차
Lithium hydroxide monohydrate (0.092 g) was added to a mixture of 4-ethoxycarbonyl-2-methoxyphenylboronic acid (0.049 g), water (1 mL) and 1,4-dioxane (1 mL), and the mixture was stirred at room temperature overnight. 2 mol/L hydrochloric acid (1.09 mL) was added to the reaction mixture, and the solvent was evaporated under reduced pressure. The residue was washed with water to afford the title compound (0.035 g).
후처리
- customthe solvent was evaporated under reduced pressure
- washThe residue was washed with water
출처 및 근거
- ORD 기록
- ord-4e49a290cc6449e9b2491cdda45e1841
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07423185B2
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