1-(2-Hydroxyethyl)piperazine → [4,5-Bis-(4-chloro-phenyl)-2-(2-ethoxy-5-trifluoromethyl-phenyl)-4,5-dihydro-imidazol-1-yl]-[4-{(4-(2-hydroxyethyl)piperazine-1-yl)methyl}phenyl]methanone

반응식

[OH:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][NH:7][CH2:6][CH2:5]1.[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([CH:17]2[CH:21]([C:22]3[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=3)[N:20]([C:29]([C:31]3[CH:36]=[CH:35][C:34]([CH2:37]Cl)=[CH:33][CH:32]=3)=[O:30])[C:19]([C:39]3[CH:44]=[C:43]([C:45]([F:48])([F:47])[F:46])[CH:42]=[CH:41][C:40]=3[O:49][CH2:50][CH3:51])=[N:18]2)=[CH:13][CH:12]=1.C(N(C(C)C)CC)(C)C>CN(C)C=O>[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([CH:17]2[CH:21]([C:22]3[CH:23]=[CH:24][C:25]([Cl:28])=[CH:26][CH:27]=3)[N:20]([C:29]([C:31]3[CH:36]=[CH:35][C:34]([CH2:37][N:7]4[CH2:8][CH2:9][N:4]([CH2:3][CH2:2][OH:1])[CH2:5][CH2:6]4)=[CH:33][CH:32]=3)=[O:30])[C:19]([C:39]3[CH:44]=[C:43]([C:45]([F:46])([F:47])[F:48])[CH:42]=[CH:41][C:40]=3[O:49][CH2:50][CH3:51])=[N:18]2)=[CH:13][CH:12]=1