Hydrochloric Acid → 6-Carbamoyl-2,3-dihydro-1,4-phthalazinedione
반응식
[C:1]([C:4]1[CH:5]=[C:6]2[C:11](=[O:12])[NH:10][C:8](=[O:9])[C:7]2=[CH:13][CH:14]=1)(=[O:3])[NH2:2].O.[NH2:16]N.Cl.O>CN1CCCC1=O>[C:1]([C:4]1[CH:5]=[C:6]2[C:7](=[CH:13][CH:14]=1)[C:8](=[O:9])[NH:16][NH:10][C:11]2=[O:12])(=[O:3])[NH2:2]참가 물질
6
실험 절차
4-Carbamoylphthalimide (2.00 g, 0.011 mol) was suspended in 12 ml of N-methyl-2-pyrrolidinone, followed by the dropwise addition of 0.8 ml of hydrazine hydrate. The obtained mixture was stirred at room temperature for 30 minutes, followed by the addition of 5.5 ml of 3N hydrochloric acid and 50 ml of water. The crystals thus precipitated were recovered by filtration, washed with water and dried with hot air. The title compound (2.0 g) was obtained as a light brown crystal (yield: 94%).
후처리
- customThe crystals thus precipitated
- filtrationwere recovered by filtration
- washwashed with water
- customdried with hot air
출처 및 근거
- ORD 기록
- ord-518c10f112d94cb6ad72531aa90f392c
- 출처 데이터셋
- uspto-grants-2001_04
- 특허 번호
- US06218392B1
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