Benzene → 2-Fluorophenyl sulfamate

HRID 327739노트

반응식

HRID 327739 반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].Cl[S:10]([N:13]=C=O)(=[O:12])=[O:11].C1C=CC=CC=1>C1(C)C=CC=CC=1>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][S:10](=[O:12])(=[O:11])[NH2:13]

참가 물질

5

반응물 3

HCID 241BenzeneHCID 97072-FluorophenolHCID 70918Chlorosulfonyl isocyanate

생성물 1

HCID 539088522-Fluorophenyl sulfamate수율 38.2%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

This compound was prepared according to the procedure of Example 56. A mixture of 11.2 g (0.1 mole) of 2-fluorophenol and 9.1 ml (14.8 g, 0.105 mole) of chlorosulfonyl isocyanate in 50 ml of toluene gave 7.3 g (38%) of the title compound as a white solid, mp 63°-64° (benzene).

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-e98fb441880b41db928d4d12bffe22b3
출처 데이터셋
uspto-grants-1993_12
특허 번호
US05273993

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