홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Hydrochloric Acid → 2-[5-[(5-Oxo-2-propyl-5,6,7,8-tetrahydro-1-naphthalenyl)oxy]pentyloxy]benzenepropanoic acid

HRID 327973
노트
인쇄 미리보기

반응식

HRID 327973 반응식
C[O:2][C:3](=[O:33])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][O:18][C:19]1[C:28]2[CH2:27][CH2:26][CH2:25][C:24](=[O:29])[C:23]=2[CH:22]=[CH:21][C:20]=1[CH2:30][CH2:31][CH3:32].[OH-].[Na+].Cl.CCOCC>CO.O>[O:29]=[C:24]1[CH2:25][CH2:26][CH2:27][C:28]2[C:19]([O:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][O:12][C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=3[CH2:5][CH2:4][C:3]([OH:33])=[O:2])=[C:20]([CH2:30][CH2:31][CH3:32])[CH:21]=[CH:22][C:23]1=2
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 14798Sodium HydroxideHCID 53803245HCID 53803245, 화합물

생성물 1

HCID 199220172-[5-[(5-Oxo-2-propyl-5,6,7,8-tetrahydro-1-naphthalenyl)oxy]pentyloxy]benzenepropanoic acid수율 100%

시약·촉매·용매 2

HCID 887
Methanol
용매
HCID 962Water용매

실험 절차

The 2-[5-[(5-oxo-2-propyl-5,6,7,8-tetrahydro-1-naphthalenyl)oxy]pentyloxy]benzenepropanoic acid methyl ester from the preceding example (1.35 g; 2.99 mmol) and 8 mL of 1N aqueous sodium hydroxide in 15 mL of methanol was stirred and refluxed for 1.5 hr. After being cooled, the resulting solution was diluted with water and acidified with 3N HCl. Work-up with ether in the usual manner gave 1.3 g (100%) 2-[5-[(5-oxo-2-propyl-5,6,7,8-tetrahydro-1-naphthalenyl)oxy]pentyloxy]benzenepropanoic acid as an orange oil.

후처리

  1. temperaturerefluxed for 1.5 hr
  2. temperatureAfter being cooled

출처 및 근거

ORD 기록
ord-dd294e758d934d3ba271014cf5c94727
출처 데이터셋
uspto-grants-1993_12
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05273999

반응 노트

불러오는 중…

이 페이지에서참가 물질실험 절차후처리출처 및 근거반응 노트