Acetone → Ethyl 2,4-dioxovalerate

HRID 330061

반응식

HRID 330061 반응식
[CH3:1][C:2]([CH3:4])=[O:3].[C:5]([O:12][CH2:13][CH3:14])(=[O:11])[C:6]([O:8]CC)=O.C(OC(OCC)OCC)C.[Cl-].[NH4+]>C(O)C>[CH3:14][CH2:13][O:12][C:5]([C:6]([CH2:1][C:2]([CH3:4])=[O:3])=[O:8])=[O:11]

참가 물질

6

반응물 4

HCID 180AcetoneHCID 7268Diethyl OxalateHCID 25517Ammonium ChlorideHCID 31214Ethyl orthoformate

생성물 1

HCID 69208Ethyl 2,4-dioxovalerate

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Ethyl acetopyruvate was prepared from acetone and diethyl oxalate as described in Org. Synthesis, Coll. Vol. 1, 238 (1958). Further reaction with triethylorthoformate and ammonium chloride in ethanol afforded the known enol ether 1. See L. Claisen, Chem. Ber., 40, 3903 (1907).

후처리

  1. customSynthesis, Coll

출처 및 근거

ORD 기록
ord-f6734b59d09746dda665bd65287785b5
출처 데이터셋
uspto-grants-1990_01
특허 번호
US04894456

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