Hydrochloric Acid → 1-((Dimethylamino)methyl)cyclopropanecarboxylic acid
반응식
C([O:3][C:4]([C:6]1([CH2:9][N:10]([CH3:12])[CH3:11])[CH2:8][CH2:7]1)=[O:5])C.[OH-].[Na+].Cl>C(O)C>[CH3:11][N:10]([CH2:9][C:6]1([C:4]([OH:5])=[O:3])[CH2:8][CH2:7]1)[CH3:12]참가 물질
5
실험 절차
To a solution of 222 mg of 1-dimethylaminomethyl-cyclopropane carboxylic acid ethyl ester in 0.4 mL of ethanol was added 0.1 mL of 5N sodium hydroxide aqueous solution, and stirred overnight at room temperature. The reaction solution was added with 0.5 mL of 1N hydrochloric acid, and the solvent and water were evaporated, to give 78 mg of a mixture of the title compound and sodium chloride as a white powder.
후처리
- customthe solvent and water were evaporated
출처 및 근거
- ORD 기록
- ord-0c5b3d9ae7dd417b88006538662a5308
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07429609B2
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