Acetic Anhydride → 1-Acetyl-5-isobutyryl-3-(ethoxy-phenyl-methylidene)-2-indolinone

HRID 347961

반응식

HRID 347961 반응식
[C:1]([C:6]1[CH:7]=[C:8]2[C:12](=[CH:13][CH:14]=1)[NH:11][C:10](=[O:15])[CH2:9]2)(=[O:5])[CH:2]([CH3:4])[CH3:3].[C:16](OC(=O)C)(=[O:18])[CH3:17].[CH3:23][CH2:24][O:25][C:26](OCC)(OCC)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>C(OCC)(=O)C.C1CCCCC1.CO>[C:16]([N:11]1[C:12]2[C:8](=[CH:7][C:6]([C:1](=[O:5])[CH:2]([CH3:4])[CH3:3])=[CH:14][CH:13]=2)[C:9](=[C:26]([O:25][CH2:24][CH3:23])[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:10]1=[O:15])(=[O:18])[CH3:17]

참가 물질

5

반응물 3

HCID 7918Acetic AnhydrideHCID 74268Benzene, (triethoxymethyl)-HCID 210846465-Isobutyryloxindole

생성물 1

HCID 689957581-Acetyl-5-isobutyryl-3-(ethoxy-phenyl-methylidene)-2-indolinone

시약·촉매·용매 1

HCID 22064753Cyclohexane ethyl acetate methanol용매

실험 절차

Prepared from 5-isobutyryl-2-indolinone, acetic anhydride and triethyl orthobenzoate Rf=0.55 (silica gel, ethyl acetate/cyclohexane/methanol 9:9:2)

출처 및 근거

ORD 기록
ord-316ac5a9490846f384ba25ac601e1cdc
출처 데이터셋
uspto-grants-2007_02
특허 번호
US07176231B2

연결된 노트

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