Acetyl chloride → 1-(6-Bromonaphthalen-2-yl)ethanone
반응식
[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[C:12](Cl)(=[O:14])[CH3:13].[Cl-].[Al+3].[Cl-].[Cl-]>[N+](C1C=CC=CC=1)([O-])=O>[Br:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:12](=[O:14])[CH3:13])[CH:8]=2)[CH:3]=1참가 물질
5
반응 조건
- 온도
- 100 °C
실험 절차
A mixture of 41.4 g of 2-bromonaphthalene, 15.7 g of acetyl chloride and 28 g of aluminum chloride in 250 ml of nitrobenzene was stirred at 100° C. for 4 hours. The reaction mixture was poured onto ice water and the resulting solid filtered off, washed with water and distilled under reduced pressure. The distillate was recrystallized from hexane to yield 2-bromo-6-acetylnaphthalene.
후처리
- additionThe reaction mixture was poured onto ice water
- filtrationthe resulting solid filtered off
- washwashed with water
- distillationdistilled under reduced pressure
- customThe distillate was recrystallized from hexane
출처 및 근거
- ORD 기록
- ord-6b8ce0e0912b4f5087e0b932e9425f44
- 출처 데이터셋
- uspto-grants-1988_08
- 특허 번호
- US04766127
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