Chloral Hydrate → 3-(1-Methylpyrrolidin-2-yl)pyridine

반응식

ClC(Cl)(Cl)C(O)O.CC1C=CC=[CH:13][C:14]=1[N:15]1[C:24](=O)[C:23]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[N:17]=[C:16]1C.CN1C(=O)CN=C(C2C=CC=CC=2)C2C=C(Cl)C=CC1=2.CCN(CCN1C(=O)CN=C(C2C=CC=CC=2F)C2C=C(Cl)C=CC1=2)CC.C1C=CC(C2(N3CCCCC3)CCCCC2)=CC=1.CNCCC(OC1C=CC(C(F)(F)F)=CC=1)C1C=CC=CC=1>>[N:15]1[CH:24]=[C:23]([CH:18]2[CH2:19][CH2:20][CH2:21][N:17]2[CH3:16])[CH:22]=[CH:13][CH:14]=1

참가 물질

반응물 6

HCID 2707Chloral Hydrate

HCID 3016Diazepam

HCID 3386Fluoxetine

HCID 3393Flurazepam

HCID 6292Methaqualone

HCID 6468Phencyclidine

생성물 1

HCID 9423-(1-Methylpyrrolidin-2-yl)pyridine

실험 절차

Depressants, for example, nonbarbiturates (e.g. bromides, chloral hydrate etc.), methaqualone, barbiturates, diazepam, flurazepam, phencyclidine, and fluoxetine;

출처 및 근거

ORD 기록: ord-2133df3f0dd1470aa69ee392e98cd43c
출처 데이터셋: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05840307

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