2,6-Dichloropyridine → 2-Chloro-6-hydrazinopyridine

HRID 358582노트

반응식

HRID 358582 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](Cl)[N:3]=1.O.[NH2:10][NH2:11]>CO>[NH:10]([C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[N:3]=1)[NH2:11]

참가 물질

4

반응물 2

HCID 169892,6-DichloropyridineHCID 24654Hydrazine hydrate (1:1)

생성물 1

HCID 3200042-Chloro-6-hydrazinopyridine

시약·촉매·용매 1

HCID 887Methanol용매2회

실험 절차

2 g of 2,6-dichloropyridine were dissolved in 60 ml of methanol and mixed with 10 ml of 80% hydrazine hydrate. The solution was firstly stirred for 3 days at room temperature and then refluxed for 10 days. Rotation in took place, the residue was taken up with methanol, followed by rotation in again and finally recrystallization from methanol/water. 0.25 g of 2-hydrazino-6-chloropyridine was obtained.

후처리

  1. temperaturerefluxed for 10 days
  2. customfinally recrystallization from methanol/water

출처 및 근거

ORD 기록
ord-c51d8063c54a4e6b814342ca1f318ddc
출처 데이터셋
uspto-grants-1991_03
특허 번호
US04997835

반응 노트

불러오는 중…