Ethanol → HCID 57087814, 화합물

HRID 361322

반응식

HRID 361322 반응식
O=[C:2]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:6]([C:13]([NH2:15])=[O:14])[C:5]2[CH:16]=[CH:17][CH:18]=[CH:19][C:4]=2[CH2:3]1.[C:20]1([NH:26][NH2:27])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C([O-])(=O)C.[Na+].C(O)C>O.Cl>[C:20]1([NH:26][N:27]=[C:2]2[C:8]3[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=3[N:6]([C:13]([NH2:15])=[O:14])[C:5]3[CH:16]=[CH:17][CH:18]=[CH:19][C:4]=3[CH2:3]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

참가 물질

7

반응물 4

HCID 702EthanolHCID 7516PhenylhydrazineHCID 34312OxcarbazepineHCID 517045Sodium Acetate

생성물 1

HCID 57087814HCID 57087814, 화합물

시약·촉매·용매 2

HCID 313Hydrochloric Acid촉매HCID 962Water용매

반응 조건

온도
60 °C

실험 절차

A mixture of 0.2 g (0.8 mmol) of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide, 0.5 g (4.6 mmol) of phenylhydrazine and 0.5 g (6 mmol) of sodium acetate in a mixture of 5 mL of water, 5 mL of ethanol and 3 drops of concentrated hydrochloric acid was heated at 60° C. for thirty minutes and then allowed to cool to room temperature. The precipitate was then filtered and washed with cold water and dilute ethanol to give the desired product as yellow crystals of m.p. 220° to 220.8° C.

후처리

  1. temperatureto cool to room temperature
  2. filtrationThe precipitate was then filtered
  3. washwashed with cold water and dilute ethanol

출처 및 근거

ORD 기록
ord-855a5c958cf4417daab61cf5df6532a4
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05866566

연결된 노트

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