Water → 1,1,7-TRICHLORO-1-HEPTEN-3-ONE

HRID 362660노트

반응식

HRID 362660 반응식
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6](Cl)=[O:7].[Cl-].[Al+3].[Cl-].[Cl-].[Cl:13][C:14]([Cl:16])=[CH2:15].O>C(Cl)Cl>[Cl:13][C:14]([Cl:16])=[CH:15][C:6](=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2][Cl:1]

참가 물질

6

반응물 4

HCID 962WaterHCID 6366Vinylidene chlorideHCID 740895-Chlorovaleryl chlorideHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 108568781,1,7-TRICHLORO-1-HEPTEN-3-ONE

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

100 g (0.62 mol) 5-Chlorovaleroyl chloride was added dropwise to 78.53 g (0.589 mmol) aluminium chloride in 150 ml methylene chloride at room temperature. After stirring for 1 hour, 45 ml (0.558 mol) 1,1-dichloroethylene in 25 ml methylene chloride was added dropwise. Under ice-cooling 100 ml water was added dropwise and solid material suction filtered on Celite. The filtrate was washed with water and the organic phase dried and concentrated. The residue was distilled in a rotary evaporator.

후처리

  1. additionwas added dropwise
  2. filtrationsolid material suction filtered on Celite
  3. washThe filtrate was washed with water
  4. customthe organic phase dried
  5. concentrationconcentrated
  6. distillationThe residue was distilled in a rotary evaporator

출처 및 근거

ORD 기록
ord-28f460e647064d609373f3b7abc6c5b6
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05869686

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