Phosphorus tribromide → 1-(Benzyloxy)-4-(bromomethyl)benzene

HRID 363023

반응식

HRID 363023 반응식
[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13]O)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.P(Br)(Br)[Br:18]>CCOCC>[CH2:1]([O:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13][Br:18])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24614Phosphorus tribromideHCID 70043(4-(Benzyloxy)phenyl)methanol

생성물 1

HCID 104927561-(Benzyloxy)-4-(bromomethyl)benzene

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

To a cold suspension of 4-benzyloxybenzyl alcohol 9-1 (21.4 g, 0.10 mol) in ether (250 ml) was added phosphorus tribromide (10.8 g, 40 mmol) as in Example 7. Recovered 27.2 g of white solid which was recrystallized from hexane (200 ml). Obtained pure bromide 9-2.

후처리

  1. customRecovered 27.2 g of white solid which
  2. customwas recrystallized from hexane (200 ml)

출처 및 근거

ORD 기록
ord-e5a47c0fc77a480b9fd05105ab39cd9c
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05872138

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