Water → 5-phenylpyridine-2-carboxylic Acid

HRID 363187

반응식

HRID 363187 반응식
[C:1]1([C:7]2[CH:8]=[N:9][C:10]([CH3:13])=[CH:11][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Mn]([O-])(=O)(=O)=[O:15].[K+].[OH2:20]>>[C:1]1([C:7]2[CH:8]=[N:9][C:10]([C:13]([OH:15])=[O:20])=[CH:11][CH:12]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 962WaterHCID 767442-Methyl-5-phenylpyridineHCID 516875Potassium Permanganate

생성물 1

HCID 27628705-phenylpyridine-2-carboxylic Acid

실험 절차

A suspension of 3-phenyl-6-methyl pyridine (1.99 g, 11.78 mmol) and potassium permanganate (7.65, 48.6 mmol), in water (50 mL) was heated at reflux for 16 hours. The reaction was allowed to cool to ambient temperature and filtered through celite to remove the solids. Acetic acid (2 mL) was added to the colourless filtrate and the product was collected as a white solid by filtration.

후처리

  1. temperatureat reflux for 16 hours
  2. filtrationfiltered through celite
  3. customto remove the solids
  4. additionAcetic acid (2 mL) was added to the colourless filtrate
  5. filtrationthe product was collected as a white solid by filtration

출처 및 근거

ORD 기록
ord-343691b2d04c48aca1c08a10cca1ee35
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05872136

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