Ethyl Acetate → Benzenebutanal, 4-(phenylmethoxy)-

HRID 363802

반응식

HRID 363802 반응식
S([O-])([O-])(=O)=O.[Mg+2].[CH:7]1[C:12]([C@@H:13](O)[CH2:14]N)=[CH:11][C:10]([OH:17])=[C:9](O)[CH:8]=1.[C:19]([O:22][CH2:23][CH3:24])(=O)[CH3:20]>[Pt]>[CH2:23]([O:22][C:19]1[CH:20]=[CH:11][C:12]([CH2:7][CH2:8][CH2:9][CH:10]=[O:17])=[CH:13][CH:14]=1)[C:24]1[CH:11]=[CH:12][CH:7]=[CH:8][CH:9]=1

참가 물질

5

반응물 3

HCID 8857Ethyl Acetate3회HCID 24083Sulfuric acid magnesium salt (1:1)HCID 439260Norepinephrine

생성물 1

HCID 11086308Benzenebutanal, 4-(phenylmethoxy)-

시약·촉매·용매 1

HCID 23939Platinum촉매

실험 절차

A solution of 4-(4-benzyloxyphenyl)-butanal (52.4 g, 206 mmol) in 150 mL ethyl acetate (1.4M solution) was prepared and set aside. 10% platinum on carbon (3.40 g) was prewetted with ethyl acetate and transferred to the reactor. To this was added magnesium sulfate (60.0 g, 500 mmol), followed by the ethyl acetate solution of (trimethylsilyl)-protected norepinephrine prepared as described in Example 1.

후처리

  1. customprepared

출처 및 근거

ORD 기록
ord-becb9cf850d841398405eae6e1336a80
출처 데이터셋
uspto-grants-1999_02
특허 번호
US05874601

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