Acetic Acid → 1,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one

HRID 364069

반응식

HRID 364069 반응식
CO[CH:3](OC)[CH2:4][NH:5][C:6](=[O:18])[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([O:16][CH3:17])[CH:9]=1.C(O)(=O)C>Cl>[CH3:15][O:14][C:11]1[C:10]([O:16][CH3:17])=[CH:9][C:8]2[CH2:7][C:6](=[O:18])[NH:5][CH:4]=[CH:3][C:13]=2[CH:12]=1

참가 물질

4

반응물 2

HCID 176Acetic AcidHCID 13092500n-(2,2-Dimethoxyethyl)-2-(3,4-dimethoxyphenyl)acetamide

생성물 1

HCID 14823731,3-Dihydro-7,8-dimethoxy-2H-3-benzazepin-2-one

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

A solution of N-(2,2-dimethoxyethyl)-3,4-dimethoxy-phenylacetamide (600.6 g) in concentrated hydrochloric acid (3 liters) is mixed with glacial acetic acid (3 liters). After being left to stand for 17 hours at ambient temperature and mixture is poured onto ice. The crystals obtained are suction filtered, washed with water until neutral and dried.

후처리

  1. waitAfter being left
  2. additionmixture is poured onto ice
  3. customThe crystals obtained
  4. washwashed with water until neutral and
  5. customdried

출처 및 근거

ORD 기록
ord-6c570c39b0344cbfbe69dbff20377c7a
출처 데이터셋
uspto-grants-1986_08
특허 번호
US04604389

연결된 노트

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