Allyl chloride → N-Allyl-N-(1,1-dimethoxyprop-2-yl)-urethane

HRID 36684

반응식

HRID 36684 반응식
[CH3:1][O:2][CH:3]([O:12][CH3:13])[CH:4]([NH:6][C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH3:5].[H-].[Na+].[H][H].[CH2:18](Cl)[CH:19]=[CH2:20]>C1(C)C=CC=CC=1>[CH2:20]([N:6]([CH:4]([CH3:5])[CH:3]([O:2][CH3:1])[O:12][CH3:13])[C:7]([O:9][CH2:10][CH3:11])=[O:8])[CH:19]=[CH2:18]

참가 물질

6

반응물 4

HCID 7850Allyl chlorideHCID 24758Sodium hydrideHCID 15069987N-(1,1-dimethoxyprop-2-yl)urethaneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 15069988N-Allyl-N-(1,1-dimethoxyprop-2-yl)-urethane

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
90 °C

실험 절차

131 g (0.686 mol) of N-(1,1-dimethoxyprop-2-yl)urethane are added dropwise to 25 g of sodium hydride (80% strength) in 700 ml of absolute toluene at 90° C. When the evolution of hydrogen has ended, 61.2 g (0.8 mol) of allyl chloride are added dropwise at 90° C and the mixture is stirred overnight at 90° C. The sodium chloride which has precipitated out is dissolved with water, the organic phase is separated off, dried over K2CO3 and concentrated and the residue is distilled.

후처리

  1. customThe sodium chloride which has precipitated out
  2. dissolutionis dissolved with water
  3. customthe organic phase is separated off
  4. dry with materialdried over K2CO3
  5. concentrationconcentrated
  6. distillationthe residue is distilled

출처 및 근거

ORD 기록
ord-b43a0c6fcedb452497400e46b1e3cb3d
출처 데이터셋
uspto-grants-1995_05
특허 번호
US05416096

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