Hydrochloric Acid → HCID 23288133, 화합물

HRID 367397노트

반응식

HRID 367397 반응식
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[C:11]1[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH:16]=1.[C:18](Cl)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.Cl>>[ClH:1].[C:18]([N:7]1[C:8]2[C:4](=[CH:3][C:2]([Cl:1])=[CH:10][CH:9]=2)[C:5]([C:11]2[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH:16]=2)=[CH:6]1)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

참가 물질

4

반응물 3

HCID 313Hydrochloric Acid2회HCID 7412Benzoyl chlorideHCID 3061874HCID 3061874, 화합물

생성물 1

HCID 23288133HCID 23288133, 화합물

실험 절차

(20 mg, 59%) from 5-chloro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4d, 25 mg, 0.1 mmol) and benzoyl chloride (21.1 mg, 0.15 mmol), m.p 256-7° C., HRMS-FAB+ for C21H19N2OCl.HCl, calculated MH+ (--HCl): 351.1264; found: 351.12595.

출처 및 근거

ORD 기록
ord-ca1f677eaa4643aaafc2534a5dedbc6d
출처 데이터셋
uspto-grants-2000_10
특허 번호
US06133287

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