Hydrogen Bromide → HCID 14938892, 화합물

HRID 3688노트

반응식

HRID 3688 반응식
[CH3:1][C:2]1[S:3][C:4]([Si](C)(C)C)=[CH:5][C:6]=1[C:7]1[C:11]([F:13])([F:12])[C:10]([F:15])([F:14])[C:9]([F:17])([F:16])[C:8]=1[C:18]1[CH:22]=[C:21]([Si](C)(C)C)[S:20][C:19]=1[CH3:27].Br>C(Cl)(Cl)Cl>[CH3:27][C:19]1[S:20][CH:21]=[CH:22][C:18]=1[C:8]1[C:9]([F:16])([F:17])[C:10]([F:14])([F:15])[C:11]([F:13])([F:12])[C:7]=1[C:6]1[CH:5]=[CH:4][S:3][C:2]=1[CH3:1]

참가 물질

4

반응물 2

HCID 260Hydrogen BromideHCID 149388931,2-Bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene

생성물 1

HCID 14938892HCID 14938892, 화합물수율 98%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

1,2-bis(2-methyl-5-trimethylsilyl-3-thienyl)hexafluorocyclopentene (2.16 g, 0.005 mol) was dissolved in chloroform (200 ml) and was allowed to react for 6 hours under refluxing conditions by adding concentrated hydrobromic acid (10 ml) to the solution. After the completion of the reaction, the chloroform layer was washed with an aqueous solution of sodium bicarbonate and the chloroform was removed under reduced pressures. The reaction product was purified by silicagel column chromatogram to give 1,2-bis(2-methyl-3-thienyl)hexafluorocyclopentene (1.8 g, 0.0049 mol).

후처리

  1. customto react for 6 hours under refluxing conditions
  2. customAfter the completion of the reaction
  3. washthe chloroform layer was washed with an aqueous solution of sodium bicarbonate
  4. customthe chloroform was removed under reduced pressures
  5. customThe reaction product was purified by silicagel column chromatogram

출처 및 근거

ORD 기록
ord-24790d511c784f0cb5c8390c2b1741e2
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05734065

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