Hydrazine hydrate (1:1) → 3-(4-Chlorophenyl)-6-hydrazinylpyridazine

HRID 372698노트

반응식

HRID 372698 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11](Cl)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.O.[NH2:16][NH2:17]>C(O)CCC>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:13]=[N:12][C:11]([NH:16][NH2:17])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 122575023-Chloro-6-(4-chlorophenyl)pyridazine

생성물 1

HCID 127268633-(4-Chlorophenyl)-6-hydrazinylpyridazine

시약·촉매·용매 1

HCID 2631-Butanol용매

실험 절차

A mixture of 10.0 g. of 6-(p-chlorophenyl)-3-chloropyridazine, 6.6 g. of hydrazine hydrate and 150 ml. of butanol is heated at reflux overnight. The reaction mixture is cooled and the precipitate is collected by filtration, washed with butanol and water and then dried yielding 6-(p-chlorophenyl)-3-hydrazinopyridazine.

후처리

  1. additionA mixture of 10.0 g
  2. temperatureat reflux overnight
  3. temperatureThe reaction mixture is cooled
  4. filtrationthe precipitate is collected by filtration
  5. washwashed with butanol and water
  6. customdried

출처 및 근거

ORD 기록
ord-b0b02fcee0a44c98a5d896154f42a7c5
출처 데이터셋
uspto-grants-1978_05
특허 번호
US04092311

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