Sec-Butylbenzene → 4'-Sec-butylbenzoin

HRID 375042

반응식

HRID 375042 반응식
O.[C:2]1([C:8]([CH:10]=[O:11])=[O:9])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:12]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)([CH2:14][CH3:15])[CH3:13]>ClC(Cl)C.[Ti](Cl)(Cl)(Cl)Cl>[CH:12]([C:16]1[CH:21]=[CH:20][C:19]([CH:10]([OH:11])[C:8](=[O:9])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:18][CH:17]=1)([CH2:14][CH3:15])[CH3:13]

참가 물질

5

반응물 2

HCID 8680Sec-ButylbenzeneHCID 12215922Glyoxal, phenyl-, hydrate

생성물 1

HCID 235130804'-Sec-butylbenzoin

시약·촉매·용매 2

HCID 24193Titanium Tetrachloride촉매HCID 63651,1-Dichloroethane용매

실험 절차

Phenylglyoxal monohydrate (304 mg, 2 mM) and sec-butylbenzene (0.62 ml, 4 mM) were dissolved in dichloroethane (4 ml), titanium tetrachloride (0.33 ml, 3 mM) was added, and reacted at room temperature for 2.5 hours. Using the same procedure as in Example 1, 4'-sec-butylbenzoin was obtained as crystal (200.6 mg, 37.3% yield).

후처리

  1. customreacted at room temperature for 2.5 hours

출처 및 근거

ORD 기록
ord-7999e189876f4d69a7d681c3c789c808
출처 데이터셋
uspto-grants-1996_01
특허 번호
US05484689

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