Fluorobenzene → HCID 53719400, 화합물

HRID 377051노트

반응식

HRID 377051 반응식
[Cl-].[Al+3].[Cl-].[Cl-].[F:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.Cl[CH:13]([Si:15]([CH3:18])([Cl:17])[Cl:16])Cl.O=P(Cl)(Cl)Cl>[Cl-].[Al+3].[Cl-].[Cl-].CCCCCC>[F:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH:13]([Si:15]([CH3:18])([Cl:17])[Cl:16])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[F:5]

참가 물질

7

반응물 4

HCID 10008FluorobenzeneHCID 24813Phosphorus oxychlorideHCID 73787Silane, dichloro(dichloromethyl)methyl-HCID 6451240Aluminum(III) Chloride

생성물 1

HCID 53719400HCID 53719400, 화합물수율 65.5%

시약·촉매·용매 2

HCID 6451240Aluminum(III) Chloride촉매HCID 8058Hexane용매2회

실험 절차

In a 100 ml, three-necked, frame dried, round bottom flask, aluminum chloride 1.679 (12.5 mmol), fluorobenzene 37.93 ml (404 mmol), and (dichloromethyl)methyldichlorosilane 7.08 ml (50.5 mmol) were reacted for 2 hours as in EXAMPLE 1. The aluminum chloride catalyst was quenched with POCl3 1.15 ml (12.5 mmol) and then stirred for another 1 hour to complete the deactivation. Freshly distilled hexane (50 ml) was added to the reaction mixture and insoluble solids in hexane were filtered from the organic solution. After hexane and fluorobenzene were distilled, the reaction products were vacuum distilled to give 10.49 g of [bis(fluorophenyl)methyl]methyldichlorosilane as a mixture of isomers (bp; 103° C./0.2 torr, yield; 65%).

후처리

  1. customIn a 100 ml, three-necked, frame dried
  2. filtrationwere filtered from the organic solution
  3. distillationAfter hexane and fluorobenzene were distilled
  4. distillationdistilled

출처 및 근거

ORD 기록
ord-97bd4a72bb3a479f9f8058ef444b5a54
출처 데이터셋
uspto-grants-2000_02
특허 번호
US06022987

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