Hydrochloric Acid → 2,2-Dimethyl-3-octenoic acid

반응식

[CH3:1][C:2]([CH3:11])([CH:5]=[CH:6][CH2:7][CH2:8][CH2:9][CH3:10])[C:3]#N.[OH-:12].[Na+].Cl.C(O)CCC.[OH2:20]>>[CH3:1][C:2]([CH3:11])([CH:5]=[CH:6][CH2:7][CH2:8][CH2:9][CH3:10])[C:3]([OH:20])=[O:12]

참가 물질

반응물 4

HCID 313Hydrochloric Acid

HCID 14798Sodium Hydroxide

HCID 22253497Water butanol

HCID 867551562,2-Dimethyl-3-octene nitrile

생성물 1

HCID 541965092,2-Dimethyl-3-octenoic acid

실험 절차

2,2-Dimethyl-3-octenoic acid is prepared by adding 2,2-dimethyl-3-octene nitrile (1.51 g, 0.01 m) to a solution prepared from 15% NaOH in butanol/H2O (2:3) (30 mL). The reaction mixture is stirred and refluxed for 7 hours, is cooled and made acidic with 10% hydrochloric acid. The reaction mixture is extracted with diethyl ether and the extract washed with saturated NaCl and dried over MgSO4, filtered and concentrated to give 2,2-dimethyl-3-octenoic acid.