Hydrochloric Acid → (2,6-Dichlorophenyl)methanesulfonamide

HRID 378981

반응식

HRID 378981 반응식
[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[C:3]=1[CH2:4][S:5](Cl)(=[O:7])=[O:6].Cl.[OH-].[NH4+:16]>>[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[C:3]=1[CH2:4][S:5]([NH2:16])(=[O:7])=[O:6]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 14923Ammonium HydroxideHCID 594465(2,6-Dichlorophenyl)methanesulfonyl chloride

생성물 1

HCID 13631936(2,6-Dichlorophenyl)methanesulfonamide수율 64%

실험 절차

The 2,6-dichlorobenzylsulfonylchloride (27 g, 103.6 mmol) in ammonium hydroxide (270 ml) was stirred at room temperature for about 3 hours. On acidification with cooled concentrated hydrochloric acid a precipitate separated and was filtered to give desired product (16 g, 64%) EI-MS m/z 239 (M−).

후처리

  1. customseparated
  2. filtrationwas filtered

출처 및 근거

ORD 기록
ord-796a401721d446ecaafb9db34d1d068f
출처 데이터셋
uspto-grants-2001_10
특허 번호
US06297265B2

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