Pyrrolidine → (E)-1-(4-bromo-2-nitrostyryl)pyrrolidine

HRID 37981

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.[NH:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1.[CH3:17]OC(OC)N(C)C>>[Br:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:17]/[N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1

참가 물질

반응물 3

HCID 31268Pyrrolidine

HCID 78373Dimethylformamide dimethyl acetal

HCID 1235464-Bromo-2-nitrotoluene

생성물 1

HCID 10913500(E)-1-(4-bromo-2-nitrostyryl)pyrrolidine

실험 절차

A solution of 4-bromo-2-nitrotoluene (100 g, 463 mmol), pyrrolidine (46.2 mL, 565 mmol), and N,N-dimethylformamide dimethylacetal (75.6 mL, 565 mmol) was refluxed for 4 hours at

출처 및 근거

ORD 기록: ord-8a881bc892ff4d0ca2036032c4b5eecd
출처 데이터셋: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08524702B2

연결된 노트

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