Methyl iodide → (2-Acetyl-4-methylpentyl)trimethylammonium Iodide

HRID 38312

반응식

HRID 38312 반응식
[I:1][CH3:2].[CH3:3][N:4]([CH2:6][CH:7]([CH2:11][CH:12]([CH3:14])[CH3:13])[C:8](=[O:10])[CH3:9])[CH3:5]>C(OCC)(=O)C>[I-:1].[C:8]([CH:7]([CH2:11][CH:12]([CH3:14])[CH3:13])[CH2:6][N+:4]([CH3:2])([CH3:5])[CH3:3])(=[O:10])[CH3:9]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 534190393-((Dimethylamino)methyl)-5-methyl-2-hexanone

생성물 1

HCID 86641883(2-Acetyl-4-methylpentyl)trimethylammonium Iodide수율 68.4%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

Iodomethane (20 g, 140.94 mmol, 2.00 equiv) was added dropwise to a solution of 3-((dimethylamino)methyl)-5-methylhexan-2-one (12 g, 70.05 mmol, 1.00 equiv) and ethyl acetate (50 mL). The solution was stirred at ambient temperature for about 16 hours., and the resulting preciptant was collected by filtration to afford the title product (15 g, yield=68%).

후처리

  1. filtration, and the resulting preciptant was collected by filtration

출처 및 근거

ORD 기록
ord-279e4411a2944fb7abb24634632e5481
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08524733B2

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