Ethanol → 1,1-Diethoxycyclohexane
반응식
[C:1]1(=O)[CH2:6][CH2:5]C[CH2:3][CH2:2]1.C1(C)C=CC(S(O)(=O)=O)=CC=1.C(O)C.[CH:22]([O:29][CH2:30][CH3:31])([O:26][CH2:27][CH3:28])OCC>O>[CH2:30]([O:29][C:22]1([O:26][CH2:27][CH3:28])[CH2:5][CH2:6][CH2:1][CH2:2][CH2:3]1)[CH3:31]참가 물질
6
실험 절차
In a round bottom flask 6 g (6.4 ml) Cyclohexanone, a pinch of p-toluene sulfonic acid and 10 ml absolute ethanol was taken. Stirred the mixture at R.T. for 5 min. Then add to it 18.12 g (20.3 ml) triethyl orthoformate and stir for 3 hr at R.T. Then distilled on rotavapour to get a thick mass. Add to it 30 ml water and extract with (25 ml×ethyl acetate, wash the organic layer with water, dried it by adding sodium sulfate and concentrate it on rotavapour to give a colorless liquid product.
후처리
- stirringstir for 3 hr at R.T
- distillationThen distilled on rotavapour
- customto get a thick mass
- extractionextract with (25 ml×ethyl acetate
- washwash the organic layer with water
- customdried it
- additionby adding sodium sulfate
- concentrationconcentrate it on rotavapour
- customto give a colorless liquid product
출처 및 근거
- ORD 기록
- ord-5f08629a6f464cdab8266a708950e8ba
- 출처 데이터셋
- uspto-grants-2014_06
- 특허 번호
- US08754207B2
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