Acetic Anhydride → 1-Acetyl-7-methylindoline

HRID 411279

반응식

HRID 411279 반응식
[CH3:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[NH:9][CH2:8][CH2:7]2.[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[C:11]([N:9]1[C:10]2[C:6](=[CH:5][CH:4]=[CH:3][C:2]=2[CH3:1])[CH2:7][CH2:8]1)(=[O:13])[CH3:12]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 123777887-Methyl-2,3-dihydro-1H-indole

생성물 1

HCID 143613661-Acetyl-7-methylindoline

실험 절차

A solution of 7-methylindoline (10.2 g) in acetic anhydride (25 ml) was refluxed for 30 min. After cooling, the reaction solution was poured into ice water (250 ml) and the resulting crystal was filtered by means of suction, heated and vacuum dried to yield the end product (11.7 g).

후처리

  1. temperatureAfter cooling
  2. filtrationthe resulting crystal was filtered by means of suction
  3. temperatureheated
  4. customvacuum dried

출처 및 근거

ORD 기록
ord-532146205184410b96c1b186bb23c4a5
출처 데이터셋
uspto-grants-2003_05
특허 번호
US06559149B1

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