Sodium Iodide → HCID 21280636, 화합물

HRID 414439

반응식

HRID 414439 반응식
[CH3:1][NH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].[I-].[Na+].Cl[CH2:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][OH:26]>C(O)CCC>[CH3:1][N:2]([CH2:18][CH2:19][O:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][OH:26])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

참가 물질

6

반응물 4

HCID 5238Sodium IodideHCID 7515N-MethylanilineHCID 11430Potassium CarbonateHCID 788712-(2-(2-Chloroethoxy)ethoxy)ethanol

생성물 1

HCID 21280636HCID 21280636, 화합물

시약·촉매·용매 1

HCID 2631-Butanol용매

실험 절차

A mixture of freshly distilled N-methylaniline (116 g, 1.1 mol), potassium carbonate (175 g, 1.25 mol), sodium iodide (4 g, 0.025 mol), 2-[2-(2-chloroethoxy)ethoxy]ethanol (168 g, 1 mol), and 900 mL of butanol was heated at reflux for 72 hours under nitrogen with vigorous stirring. After cooling and filtration the butanol was evaporated at reduced pressure to leave a tan oil. The oil was fractionally distilled in vacuo, yielding 150 g (63%) as a colorless oil, bp 190°-191° C. (0.13 mm).

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 72 hours under nitrogen with vigorous stirring
  3. temperatureAfter cooling
  4. filtrationfiltration the butanol
  5. customwas evaporated at reduced pressure
  6. customto leave a tan oil
  7. distillationThe oil was fractionally distilled in vacuo
  8. customyielding 150 g (63%) as a colorless oil, bp 190°-191° C. (0.13 mm)

출처 및 근거

ORD 기록
ord-d37f2b412cce47ea9333d02b28415777
출처 데이터셋
uspto-grants-1988_12
특허 번호
US04792208

연결된 노트

불러오는 중…