Homoallyl bromide → Diethyl 3-butenylphosphonate

HRID 417171노트

반응식

HRID 417171 반응식
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[P:6]([O:13]CC)([O:10][CH2:11][CH3:12])[O:7][CH2:8][CH3:9]>C(Cl)(Cl)Cl>[CH2:2]([P:6](=[O:13])([O:10][CH2:11][CH3:12])[O:7][CH2:8][CH3:9])[CH2:3][CH:4]=[CH2:5]

참가 물질

4

반응물 2

HCID 21241Homoallyl bromideHCID 31215Triethyl phosphite

생성물 1

HCID 10997850Diethyl 3-butenylphosphonate

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

1-bromo-3-butene (39.0 mmol) and triethyl phosphite (1 g, 6 mmol) were dissolved and reacted in CHCl3 (30 mL). Then, the reaction solution was refluxed for 12 hours, cooled to room temperature and filtered through a glass filter. Chloroform (CHCl3) was completely removed from the solution under vacuum to thereby give an oily compound as the title compound. The 1H NMR results of the compound thus obtained are given as follows.

후처리

  1. temperatureThen, the reaction solution was refluxed for 12 hours
  2. filtrationfiltered through a glass
  3. filtrationfilter
  4. customChloroform (CHCl3) was completely removed from the solution under vacuum

출처 및 근거

ORD 기록
ord-4a261f2dbf654a348991f1f703983f8c
출처 데이터셋
uspto-grants-2012_01
특허 번호
US08089682B2

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