Styrene → trans-Stilbene

HRID 429609

반응식

HRID 429609 반응식
[CH2:1]=[CH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.Cl[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[C:3]1(/[CH:2]=[CH:1]/[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:3]1(/[CH:2]=[CH:1]\[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:3]1([C:2]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH2:1])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

참가 물질

5

반응물 2

HCID 7501StyreneHCID 7964Chlorobenzene

생성물 3

HCID 107401,1-Diphenylethylene수율 12.4%HCID 638088trans-Stilbene수율 86.7%HCID 5356785cis-Stilbene수율 0.9%

반응 조건

온도
150 °C

실험 절차

A reaction is performed as described in Example 1, except that 102.8 mg (0.99 mmol) of styrene and 164.8 mg (1.46 mmol) of chlorobenzene are used, and the reaction mixture is stirred at 150° C. for 5.5 hours. With 94.6% conversion of Cl-benzene, an 82.1% yield of Heck products (86.7% trans-stilbene, 0.9% cis-stilbene, 12.4% 1,1-diphenylethene) is obtained.

출처 및 근거

ORD 기록
ord-0f3dd49aeb5e4d00b6d810eb17ec34cb
출처 데이터셋
uspto-grants-2001_11
특허 번호
US06316675B1

연결된 노트

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