Benzene, 1-chloro-4-ethynyl- → Z-4-chlorostyryl 2-chlorobenzylsulfide

HRID 431149

반응식

HRID 431149 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]#[CH:9])=[CH:4][CH:3]=1.[Cl:10][C:11]1[CH:18]=[CH:17][CH:16]=[CH:15][C:12]=1[CH2:13][SH:14].[Na]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]\[CH:13]([S:14][CH:13](/[CH:9]=[CH:8]\[C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[C:12]2[CH:15]=[CH:16][CH:17]=[CH:18][C:11]=2[Cl:10])[C:12]2[CH:15]=[CH:16][CH:17]=[CH:18][C:11]=2[Cl:10])=[CH:4][CH:3]=1

참가 물질

4

반응물 3

HCID 70118Benzene, 1-chloro-4-ethynyl-HCID 5807592-Chlorobenzyl mercaptanHCID 5360545Sodium

생성물 1

HCID 86588938Z-4-chlorostyryl 2-chlorobenzylsulfide

실험 절차

A solution of 4-chlorophenylacetylene (0.02 mol) and 2-chlorobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) was subjected to Procedure 2 to form (Z)-4-chlorostyryl 2-chlorobenzylsulfide. The title compound was obtained in 73% yield following oxidation. 1HNMR (CDC13) δ4.56 (2H, s), 6.70 (1H, d, JH,H=12.05), 7.18-7.64 (8H aromatic+1H ethylenic).

출처 및 근거

ORD 기록
ord-7d2388c45870420b822bfdc985adb262
출처 데이터셋
uspto-grants-2003_12
특허 번호
US06656973B2

연결된 노트

불러오는 중…