Hydrazine hydrate (1:1) → HCID 18763424, 화합물

HRID 431382노트

반응식

HRID 431382 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:19]=[CH:20][C:21]=1[Cl:22])[O:5][CH2:6][C:7]1[CH:8]=[C:9]([N+:16]([O-])=O)[CH:10]=[C:11]([N+:13]([O-])=O)[CH:12]=1.O.NN>CO.[Ni]>[Cl:1][C:2]1[CH:3]=[C:4]([CH:19]=[CH:20][C:21]=1[Cl:22])[O:5][CH2:6][C:7]1[CH:8]=[C:9]([NH2:16])[CH:10]=[C:11]([NH2:13])[CH:12]=1

참가 물질

5

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 187634315-(3,4-Dichlorophenoxymethyl)-1,3-dinitrobenzene

생성물 1

HCID 18763424HCID 18763424, 화합물

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

5-(3,4-dichlorophenoxymethyl)-1,3-dinitrobenzene in 5 ml MeOH was added to a solution of 10 ml 2.5 mmole hydrazine monohydrate and catalytic amount of Ra—Ni. The mixture was stirred under reflux for 30 min and then cooled to room temperature. GC-MS gave the peak of reduced product. The solution was filtered through Celite and MeOH was evaporated with rotaevaporation. The residue was used directly for next step without further purification.

후처리

  1. temperatureunder reflux for 30 min
  2. customGC-MS gave the peak of reduced product
  3. filtrationThe solution was filtered through Celite and MeOH
  4. customwas evaporated with rotaevaporation
  5. customThe residue was used directly for next step without further purification

출처 및 근거

ORD 기록
ord-c09c85f942a7469e92ec2d9fdf50c5f7
출처 데이터셋
uspto-grants-2003_12
특허 번호
US06656971B2

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