Tetrahydrothiophene → Methyl-tetrahydrothiophene triflate

HRID 43294

반응식

HRID 43294 반응식
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:6][O:7][S:8]([C:11]([F:14])([F:13])[F:12])(=[O:10])=[O:9]>ClCCl>[OH:10][S:8]([C:11]([F:14])([F:13])[F:12])(=[O:9])=[O:7].[CH3:6][CH:2]1[CH2:3][CH2:4][CH2:5][S:1]1

참가 물질

4

반응물 2

HCID 1127TetrahydrothiopheneHCID 9526Methyl triflate

생성물 1

HCID 87659244Methyl-tetrahydrothiophene triflate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

11 mmol of tetrahydrothiophene was dissolved in 10 ml of dichloromethane at 0° C., and about 12 mmol of methyltrifluoromethane sulfonate was slowly dripped to the mixture. As a result, a white solid product in a salt form was obtained after about 5 minutes. The solid product was filtered and dried for 1 hour in an oven at 50° C. to obtain the following product:

후처리

  1. customAs a result, a white solid product in a salt form was obtained after about 5 minutes
  2. filtrationThe solid product was filtered
  3. customdried for 1 hour in an oven at 50° C.
  4. customto obtain the following product

출처 및 근거

ORD 기록
ord-9dffcd1064074e23ac42b75b8afab9eb
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536347B2

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