Ammonia → 2-Ethynylnaphthalene

HRID 436676

반응식

HRID 436676 반응식
[CH:1]([C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1)=[CH2:2].BrBr.N.[NH2-].[Na+]>C(Cl)(Cl)Cl>[C:1]([C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1)#[CH:2]

참가 물질

6

반응물 4

HCID 222AmmoniaHCID 132302-VinylnaphthaleneHCID 24408Bromine2회HCID 24533Sodium amide

생성물 1

HCID 1150172-Ethynylnaphthalene

시약·촉매·용매 1

HCID 6212Chloroform용매2회

실험 절차

To a mixture of 15.5 g. of 2-vinylnaphthalene and 300 ml. of chloroform, a 5 percent bromine in chloroform solution is added at -10° C until the bromine color persists. The mixture is then added to 200 ml. of ammonia containing 15 g. of sodium amide. The mixture is allowed to evaporate, acidified with dilute hydrochloric acid, and the residue is extracted with diethyl ether. The extracts are combined, washed to neutrality with water, dried, and evaporated to yield 2-ethynylnaphthalene.

후처리

  1. additionTo a mixture of 15.5 g
  2. additionThe mixture is then added to 200 ml
  3. customto evaporate
  4. extractionthe residue is extracted with diethyl ether
  5. washwashed
  6. customdried
  7. customevaporated

출처 및 근거

ORD 기록
ord-468a3d89d2554877aa82ccae515f5a6d
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04009197

연결된 노트

불러오는 중…