Hydrochloric Acid → 2-Cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

HRID 439561노트

반응식

HRID 439561 반응식
[OH-].[Na+].[C:3]([CH2:5][C:6]([OH:8])=[O:7])#[N:4].[OH:9][C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][C:17]=1[OH:18])[CH:13]=O.Cl>>[C:3]([C:5](=[CH:13][C:12]1[CH:15]=[CH:16][C:17]([OH:18])=[C:10]([OH:9])[CH:11]=1)[C:6]([OH:8])=[O:7])#[N:4]

참가 물질

5

반응물 4

HCID 313Hydrochloric AcidHCID 87683,4-DihydroxybenzaldehydeHCID 9740Cyanoacetic acidHCID 14798Sodium Hydroxide

생성물 1

HCID 20542-Cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid

실험 절차

To 2N aqueous sodium hydroxide solution (175 ml, 350 mmol) heated at 60° C. were added cyanoacetic acid (7.2 g, 86.7 mmol) and 3, 4-dihydroxybenzaldehyde (12.0 g, 86.9 mmol), and the resulting mixture was stirred for 30 minutes. The reaction mixture was allowed to cool at room temperature and gradually mixed with dilute hydrochloric acid until the reaction mixture became acidic. The product was filtered and dried to give α-cyano-3, 4-dihydroxycinnamic acid (hereinafter referred to as "Compound A" (10.0 g, 56% in yield).

후처리

  1. filtrationThe product was filtered
  2. customdried

출처 및 근거

ORD 기록
ord-83702e63595e4e26b6951b6bf4ae4186
출처 데이터셋
uspto-grants-1996_05
특허 번호
US05514711

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