Hydrochloric Acid → N-(4-carboxy-phenyl)-N-methyl-terephthalamic acid

HRID 440820노트

반응식

HRID 440820 반응식
C[O:2][C:3](=[O:24])[C:4]1[CH:23]=[CH:22][C:7]([C:8]([N:10]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20]C)=[O:19])=[CH:14][CH:13]=2)[CH3:11])=[O:9])=[CH:6][CH:5]=1.[OH-].[Na+].Cl>C(#N)C>[C:18]([C:15]1[CH:14]=[CH:13][C:12]([N:10]([CH3:11])[C:8](=[O:9])[C:7]2[CH:22]=[CH:23][C:4]([C:3]([OH:24])=[O:2])=[CH:5][CH:6]=2)=[CH:17][CH:16]=1)([OH:20])=[O:19]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 54006989N-(4-methoxycarbonylphenyl)-N-methyl-terephthalamic acid methyl ester

생성물 1

HCID 22404898N-(4-carboxy-phenyl)-N-methyl-terephthalamic acid

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

0.99 g of N-(4-methoxycarbonylphenyl)-N-methyl-terephthalamic acid methyl ester was dissolved in 10 ml of acetonitrile and treated with 10 ml of 1N sodium hydroxide solution and the reaction mixture was stirred at room temperature for 16 hours. The mixture was then acidified with 1N hydrochloric acid and the resulting precipitate was filtered off yielding N-(4-carboxy-phenyl)-N-methyl-terephthalamic acid, which was used directly in the next step.

후처리

  1. filtrationthe resulting precipitate was filtered off

출처 및 근거

ORD 기록
ord-148c016425eb4d998ae972f565a68b75
출처 데이터셋
uspto-grants-1996_05
특허 번호
US05521160

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