Phenyl 2-chloro-2-oxoacetate → Carbonochloridic acid, 4-methoxyphenyl ester

HRID 443082

반응식

HRID 443082 반응식
[Cl:1]C(=O)C(OC1C=CC=CC=1)=O.ClC(=O)[C:15]([O:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)=[O:16]>[Cl-].C1([P+](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>[Cl:1][C:15]([O:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)=[O:16]

참가 물질

4

반응물 2

HCID 11423990Phenyl 2-chloro-2-oxoacetateHCID 537064644-Methoxyphenyl chloroglyoxylate

생성물 1

HCID 82128Carbonochloridic acid, 4-methoxyphenyl ester

시약·촉매·용매 1

HCID 164911Tetraphenylphosphonium Chloride촉매

실험 절차

The decarbonylation reaction was repeated in the manner as described in Example 70, except that the amount of tetraphenylphosphonium chloride was changed as set forth in Table 11, that the phenyl chloroglyoxylate was replaced with 1.396 mmol. of 4-methoxyphenyl chloroglyoxylate (4-MeO--PCG), and that the reaction temperature and reaction period were changed as set forth in Table 11. The results are also set forth in Table 11.

후처리

  1. customThe decarbonylation reaction

출처 및 근거

ORD 기록
ord-d83da159e16c4b9983a417cd4ed1f36c
출처 데이터셋
uspto-grants-1999_04
특허 번호
US05892091

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