Acetyl chloride → 1-(4-Propylphenyl)ethan-1-one

HRID 443680

반응식

HRID 443680 반응식
[Cl-].[Cl-].[Cl-].[Al+3].[C:5](Cl)(=[O:7])[CH3:6].[CH3:9][CH2:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1>C(=S)=S>[CH3:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([C:5]([CH3:6])=[O:7])=[CH:14][CH:13]=1

참가 물질

5

반응물 3

HCID 6367Acetyl chlorideHCID 7668PropylbenzeneHCID 6451240Aluminum(III) Chloride2회

생성물 1

HCID 762361-(4-Propylphenyl)ethan-1-one

시약·촉매·용매 1

HCID 6348Carbon Disulfide용매2회

실험 절차

Crushed anhydrous aluminium trichloride (1.28 mole) was suspended in dry carbon disulphide (348 ml). Acetylchloride (1.1 mole) and n-propylbenzene (1.0 mole) was dissolved in dry carbon disulphide (348 ml) and added to the suspension of aluminium trichloride under anhydrous conditions. The mixture was then left to stir overnight. The solvent was distilled from the reaction mixture and the viscous residue poured onto crushed ice and stirred for 0.5 hours. The product was extracted into ether and the extract washed with water and dried (Na2SO4). The ether was removed by distillation and the oily residue distilled. The product had mpt 132° C. at 0.1 mm Hg.

후처리

  1. waitThe mixture was then left
  2. distillationThe solvent was distilled from the reaction mixture
  3. additionthe viscous residue poured
  4. customonto crushed ice
  5. stirringstirred for 0.5 hours
  6. extractionThe product was extracted into ether
  7. washthe extract washed with water
  8. dry with materialdried (Na2SO4)
  9. customThe ether was removed by distillation
  10. distillationthe oily residue distilled

출처 및 근거

ORD 기록
ord-183b8cdcf9c34c478cd67ba56997d885
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04261651

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